PineTree Therapeutics, Inc.
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AbReptor™

AbReptor is a first and best-in-class, transformative and modular bi-specific and multi-specific antibody platform designed to degrade membrane-bound and extracellular proteins. 

AbReptor works by co-engaging a surface-receptor or extracellular protein of interest together with another proprietary receptor target.  
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  • TPD Platform – Targeted Protein Degradation

  • Antibody-based platform combines direct tumor targeting with immuno-oncology in single molecule

  • Platform to generate multispecific antibodies to degrade kinase and non-kinase receptors

  • Potentially applicable to all oncogenic receptor tyrosine kinases and immune checkpoint inhibitors
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  • Ability to address key unmet needs of drug resistance and tumor recurrence
Pinetree Therapeutics
West Cambridge Scientific Park
767C Concord Ave
Cambridge MA 02138


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  • HOME
  • SCIENCE
    • AbReptor
    • Taer-Tab
  • TEAM
    • Pinetree Team
    • Leadership Bios
  • NEWS
  • CAREERS
  • CONTACT