AbReptor™

AbReptor is a first and best-in-class, transformative and modular bi-specific and multi-specific antibody platform designed to degrade membrane-bound and extracellular proteins. 

AbReptor works by co-engaging a surface-receptor or extracellular protein of interest together with another proprietary receptor target.  

• TPD Platform – Targeted Protein Degradation
  
  
• Antibody-based platform combines direct tumor targeting with immuno-oncology in single molecule
  
  
• Platform to generate multispecific antibodies to degrade kinase and non-kinase receptors
  
  
• Potentially applicable to all oncogenic receptor tyrosine kinases and immune checkpoint inhibitors
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• Ability to address key unmet needs of drug resistance and tumor recurrence